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1. Batch–flow hybrid synthesis of the antipsychotic clozapine

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   10 May 2024 | Contributor(s):: Neyt, N.C., Riley, D.L.

   The development of batch–flow hybrid processes is becoming an attractive prospect through which chemists can make use of the best aspects of both technologies. We have reported the implementation of an on-the-fly purification by trituration which can also be utilised to perform solvent swaps. We...