Skip to main content
Prepare for an exciting September! Each week, we'll examine the latest trends in PAT, offering fresh insights straight from recent conferences. Your perspective matters, so we encourage you to share your thoughts as well. Stay informed, stay engaged, and let's explore these cutting-edge developments together. https://bit.ly/3Xw0X7k
3.144.26.126

A segmented flow platform for on-demand medicinal chemistry and compound synthesis in oscillating droplets

By Hwang, YJ; Coley, CWAbolhasani, M; Marzinzik, AL; Koch, G; Spanka, C; Lehmann, H; Jensen, KF

View Resource (DOI)

Category

Peer-reviewed journal

Published on CMKC

Abstract

We report an automated flow chemistry platform that can efficiently perform a wide range of chemistries, including single/multi-phase and single/multi-step, with a reaction volume of just 14 mu L. The breadth of compatible chemistries is successfully demonstrated and the desired products are characterized, isolated, and collected online by preparative HPLC/MS/ELSD.

Journal

Chemical Communications. Volume 53, 2017, 6649-6652

DOI

10.1039/c7cc03584e

Type of publication

Peer-reviewed journal

Affiliations

  • Massachusetts Institute of Technology (MIT) (MIT)
  • Inha University
  • North Carolina State University; Novartis Institute for Biomedical Research

Article Classification

Research Article

Classification Areas

  • API

Tags

  1. API
  2. Automated flow chemistry platform
  3. Preparative HPLC
  4. Research Article
  5. single/multiphase
  6. single multistage