Skip to main content
Join CMKC members for a complimentary virtual event on December 10, 11am ET: CM MythBusters: https://bit.ly/3YXJynA. This is a fantastic opportunity to connect, collaborate, and debunk common myths about continuous manufacturing!
18.117.75.218

An automated modular assembly line for drugs in a miniaturized plant

By Hu, Chuntian; Testa, Christopher; Wu, Wei; Shvedova, Khrystyna; Shen, Dongying; Sayin, Ridade; . Halkude, Bhakti; Casati, Federica; Hermant, Paul; Ramnath, Anjana; Born, Stephen; Takizawa, Bayan; O'Connor, Thomas; Yang, Xiaochuan; Ramanujamd, Sukumar; Mascia, Salvatore

Published on

Abstract

We report here a fully automated, end-to-end, integrated continuous manufacturing process for a small-molecule generic medication with built-in quality assurance. The entire process fits into a box of 30.7 m2 modular footprint and a total residence time of less than 30 h, with a throughput up to 40.3 x10-6 tablets per year

Journal

Chemical Communications. Volume 7, 2020

DOI

10.1039/c9cc06945c

Type of publication

Peer-reviewed journal

Affiliations

  • Continuus Pharmaceuticals
  • IMA S.p.A.
  • Food and Drug Administration (FDA)USV Private Limited

Article Classification

Other

Classification Areas

  • PAT
  • Oral solid dose

Tags