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Bachem - Insights into Peptide Chemistry Achievements by the World's Leading Independent Manufacturer of Peptides

By Mergler, M; Loidl, GDiekmann, M; Dick, F

Published on

Abstract

The Swiss fine chemicals company Bachem, pioneer and specialist in the chemical synthesis of peptides, has also become an internationally leading manufacturer of peptide active pharmaceutical ingredients (APIs). In response to increasing demands in scale and purity, Bachem's Research Article efforts centered on the chemistry involved in solid-phase peptide synthesis and the production of the required amino acid derivatives with the aim of a continuous improvement of the technology. The resulting optimized protocols together with high-throughput equipment enabled us to manufacture long peptide APIs and, more recently, even pharma-grade glycoproteins in industrial scale.

Journal

Chimia. Volume 67, 2013, 874-880

DOI

10.2533/chimia.2013.874

Type of publication

Peer-reviewed journal

Affiliations

  • Bachem AG

Article Classification

Research Article

Classification Areas

  • API

Tags