The way organic multistep synthesis is performed is changing due to the adoption of flow chemical techniques, which has enabled the development of improved methods to make complex molecules. The modular nature of the technique provides not only access to target molecules via linear flow approaches but also for the targeting of structural cores with single systems. This perspective article summarizes the state of the art of continuous multistep synthesis and discusses the main challenges and opportunities in this area.

• Max Planck Institute for Colloids and Interfaces
• Free University of Berlin

• API

1. Active pharmaceutical ingredients
2. API
3. chemical assembly systems
4. continuous multistep synthesis
5. flow chemistry
6. Review article