Seeded droplet microfluidic system for small molecule crystallization
Contributor(s):: Garg, N, Tona, RMartin, P, Martin-Soladana, PM, Ward, G, Douillet, N, Lai, D
A microfluidic approach to seeded crystallization has been demonstrated using abacavir hemisulfate, a nucleoside analog reverse transcriptase inhibitor, in droplet reactors to control polymorphism and produce particles with a low particle size distribution. Two techniques are introduced: (1) the...