Comprehensive modelling of pharmaceutical solvation energy in different solvents
09 Jun 2023 | Contributor(s):: Panwar, A, Shirazian, SSingh, M, Walker, GM
Crystallization is an important processing step in production of active pharmaceutical ingredients (API). This process is used to recover/separate the synthesized APIs for further processing to final solid dosage oral formulations. Control and understanding of crystallization are of great...
Artificial neural network modelling of continuous wet granulation using a twin-screw extruder
09 Jun 2023 | Contributor(s):: Shirazian, Saeed, Kuhs, Manuel, Darwish, Shaza, Croker, Denise., Walker, Gavin M
Computational modelling of twin-screw granulation was conducted by using an artificial neural network (ANN) approach. Various ANN configurations were considered with changing hidden layers, nodes and activation functions to determine the optimum model for the prediction of the process. The neural...