Pharmaceutical crystallisation processes from batch to continuous operation using MSMPR stages: Modelling, design, and control
Contributor(s):: Su, Qinglin, Nagy, Zoltan K., Rielly, Chris D.
In pharmaceuticals manufacturing, the conversion of conventional batch crystallisations to continuous mode has the potential for intensified, compact operation and more consistent production via quality-by-design. A pragmatic conversion approach is to utilise existing stirred tank batch...
Advanced methodologies for cocrystal synthesis
Contributor(s):: Douroumis, D, Ross, SA, Nokhodchi, A
Pharmaceutical cocrystals are multicomponent systems composed of two or more molecules and held together by H-bonding. Currently, cocrystals provide exciting opportunities in the pharmaceutical industry for the development and manufacturing of new medicines by improving poor physical properties...