Integrated multi-step continuous flow synthesis of daclatasvir without intermediate purification and solvent exchange
24 Apr 2024 | Contributor(s):: Rana, Abhilash, Mahajan, Bhushan, Ghosh, Subhash, Srihari, Pabbaraja, Singh, Ajay K.
The rapid transmission of viral diseases can cause massive economic damage and loss of life. The manufacture of most anti-viral drugs is normally carried out using batch synthesis which typically requires long production times (3–15 days) and significant manpower and infrastructure. The...