Towards 4th industrial revolution efficient and sustainable continuous flow manufacturing of active pharmaceutical ingredients
09 Jun 2023 | Contributor(s):: Sagandira, CR, Nqeketo, SMhlana, K, Sonti, T, Gaqa, S, Watts, P
Continuous flow chemistry has opened a new paradigm in both the laboratory and pharmaceutical industry. This review details the recently reported literature on continuous multistep telescoped synthesis of active pharmaceutical ingredients (APIs), inline flow downstream processing, in-process...
Comprehensive modelling of pharmaceutical solvation energy in different solvents
09 Jun 2023 | Contributor(s):: Panwar, A, Shirazian, SSingh, M, Walker, GM
Crystallization is an important processing step in production of active pharmaceutical ingredients (API). This process is used to recover/separate the synthesized APIs for further processing to final solid dosage oral formulations. Control and understanding of crystallization are of great...