Evaluating the potential for optimization of axial back-mixing in continuous pharmaceutical manufacturing
Contributor(s):: Peterwitz, M, Schembecker, G
In continuous pharmaceutical manufacturing, the degree of back-mixing has two contrary effects on the propagation of disturbances through a process. Firstly, back-mixing results in the contamination of adjacent material by strong disturbances and additional losses. However, the available...
Challenges in tracing material flow passing a loss-in-weight feeder in continuous manufacturing processes
Contributor(s):: Peterwitz, Moritz, Gerling, Sina, Schembecker, Gerhard
Loss-in-weight feeders are an integral part of most continuous manufacturing processes, ensuring a constant mass flow. The feeders cause a significant degree of back-mixing in such lines. Understanding back-mixing is essential for the treatment of disturbances. However, feeders refilled...