Integrated continuous manufacturing in pharmaceutical industry: current eolutionary steps toward revolutionary future
Contributor(s):: Nada A Helal, Ola Elnoweam, Heba Abdullah Eassa, Ahmed M Amer, Mohamed Ashraf Eltokhy, Mohamed A Helal, Heba A Fayyaz, Mohamed Ismail Nonou
Continuous manufacturing (CM) has the potential to provide pharmaceutical products with better quality, improved yield and with reduced cost and time. Moreover, ease of scale-up, small manufacturing footprint and on-line/in-line monitoring and control of the process are other merits for CM....
Design and operation of a filter reactor for continuous production of a selected pharmaceutical intermediate
Contributor(s):: Christensen, KM, Pedersen, MJDam-Johansen, K, Holm, TL, Skovby, T, Kiil, S
A novel filter reactor system for continuous production of selected pharmaceutical intermediates is presented and experimentally verified. The filter reactor system consists of a mixed flow reactor equipped with a bottom filter, to retain solid reactant particles, followed by a conventional plug...