Using Residence Time Distributions (RTDs) to Address the Traceability of Raw Materials in Continuous Pharmaceutical Manufacturing
09 Jun 2023 | Contributor(s):: Engisch, William, Muzzio, Fernando
Continuous processing in pharmaceutical manufacturing is a relatively new approach that has generated significant attention. While it has been used for decades in other industries, showing significant advantages, the pharmaceutical industry has been slow in its adoption of continuous processing,...
Measurement of residence time distributions and material tracking on three continuous manufacturing lines
09 Jun 2023 | Contributor(s):: Karttunen, Anssi-Pekka, Hörmannb,Theresa, De Leersnyder, Fien, Ketolainen, Jarkko, De Beer, Thomas, Hsiao, Wen-Kai, Korhonen, Ossi
Over the recent decade, benefits of continuous manufacturing (CM) of pharmaceutical products have been acknowledged widely. In contrast to batch processes, the product is not physically separated into batches in CM, which creates a few challenges. Product release is done for batches that should...