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1. Examining drug hydrophobicity in continuous wet granulation within a twin screw extruder

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   09 Jun 2023 | Contributor(s):: Li, H., Thompson, M. R., O'Donnell, K. P.

   The influence of active pharmaceutical ingredient (API) hydrophobicity on continuous wet granulation was studied in twin screw granulation utilizing foamed binder delivery. The APIs examined were caffeine, acetaminophen, ibuprofen and griseofulvin and the drug load was maintained constant at 15...