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  1. On-line monitoring of blend uniformity in continuous drug product manufacturing process -The impact of powder flow rate and the choice of spectrometer: Dispersive vs. FT

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    Contributor(s):: Shi, Zhenqi, McGhehey, Kathryn C, Leavesley, Ian M., Manley, Leo F.

    One of the commonly acknowledged issues in continuous manufacturing of drug products is how to provide a representative sampling on flowing powder to assure its blend uniformity. An investigation was conducted to improve understanding on the impact of powder flow rate under different continuous...