Population Balance Model Development Verification and Validation of Cooling Crystallization of Carbamazepine
Contributor(s):: Liu, Yiqing C., Acevedo, David Yang, Xiaochuan Naimi, Sean, Wu, Wei-Lee, Pavurala, Naresh, Nagy, Zoltan K., O'Connor, Thomas F.
Using process modeling to understand process dynamics and potentially explore the design space of a crystallization process is difficult because of its complex nature with many factors at play, such as initial concentration, supersaturation, seeding strategy, and flow pattern. In this work, a...