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1. Indirect monitoring of ultralow dose API content in continuous wet granulation and tableting by machine vision

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   Contributor(s):: Ficzere, Máté, Mészáros, Lilla Alexandra, Madarász, Lajos, Novák, Márk, Nagy, Zsombor Kristóf, Galata, Dorián László

   This paper presents new machine vision–based methods for indirect real-time quantification of ultralow drug content during continuous twin-screw wet granulation and tableting. Granulation was performed with a solution containing carvedilol (CAR) as API in the ultralow dose range (0.05 w/w% in the...