Flow and bulk density enhancements of pharmaceutical powders using a conical screen mill: A continuous dry coating device
Contributor(s):: Huang, ZH, Scicolone, JV, Gurumuthy, L, Dave, RN
The conical screen mill or Comil, a powder delumping device, was investigated due to its recent success as a continuously operated dry coater, The improvements in packing and flowability for different size grades of active pharmaceutical ingredients (APls) (acetaminophen, ibuprofen, and ascorbic...
Effects of Coating Materials and Processing Conditions on Flow Enhancement of Cohesive Acetaminophen Powders by High-Shear Processing With Pharmaceutical Lubricants
Contributor(s):: Wei, GG, Mangal, S, Denman, J, Gengenbach, T, Bonar, KL, Khan, RI, Qu, L, Li, TL, Zhou, Q
This study has investigated the surface coating efficiency and powder flow improvement of a model cohesive acetaminophen powder by high-shear processing with pharmaceutical lubricants through 2 common equipment, conical comil and high-shear mixer. Effects of coating materials and processing...