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Real-time monitoring of particle size distribution in a continuous granulation and drying process by near infrared spectroscopy
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09 Jun 2023 | Contributor(s):: Pauli, V, Roggo, YKleinebudde, P, Krumme, M
In continuous granulation, it can be important to control granules particle size distribution (PSD), as it may affect final product quality. Near infrared spectroscopy (NIRS) is already a routine analytical procedure within pharmaceutical continuous manufacturing for the in-line analysis of...