Synthesis of the Antibiotic Precursor Thiazolyl-7-Aminocephalosporanic Acid in a Microstructured Flow System
Contributor(s):: Wirth, Vanessa, Volkmar, Julia, Bayer, Thomas
The synthesis of thiazolyl-7-aminocephalosporanic acid, a pharmaceutical precursor of the β-lactam antibiotic drug cefodizime, could be successfully realized in a continuous microstructured flow system. This was accomplished by changing the process window from batch, having a reaction temperature...