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1. Continuous Manufacturing: Many Want It, But Here's Why Few Have It

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   Website | 20 Feb 2024 | Contributor(s):: Ioanna Deni

   Continuous manufacturing remains a key objective among bioprocessing professionals. While continuous bioprocessing isn’t a new concept, having been applied in the production of both old and new products, significant technological advancements set the stage for its wider adoption.

2. The route from problem to solution in multistep continuous flow synthesis of pharmaceutical compounds

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   Peer-reviewed journal | 09 Jun 2023 | Contributor(s):: Bana, P, Orkenyi, RLovei, K, Lako, A, Turos, GI, Eles, J, Faigl, F, Greiner, I

   Recent advances in the field of continuous flow chemistry allow the multistep preparation of complex molecules such as APIs (Active Pharmaceutical Ingredients) in a telescoped manner. Numerous examples of laboratory-scale applications are described, which are pointing towards novel manufacturing...

3. Continuous purification of active pharmaceutical ingredients using multistage organic solvent nanofiltration membrane cascade

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   Peer-reviewed journal | 09 Jun 2023 | Contributor(s):: Peeva, L, Burgal, JDValtcheva, I, Livingston, AG

   Downstream processing accounts for a large fraction of the production costs in pharmaceutical manufacturing. Organic solvent nanofiltration performed in a membrane cascade offers an interesting possibility for a continuous downstream processing unit operation. This work demonstrates continuous...