Separation and Purification in the Continuous Synthesis of Fine Chemicals and Pharmaceuticals
Contributor(s):: O'Mahony, M, Ferguson, SStelzer, T, Myerson, A
The use to both chemists and chemical engineers working in flow synthesis, this chapter provides a summary of separation and purification operations that can be applied to flow synthesis reaction streams. Both single and biphasic separations for the liquid phase are detailed. Separation and...
Characterization of a Modular Continuous Vacuum Screw Filter for Small-Scale Solid-Liquid Separation of Suspensions
Contributor(s):: Steenweg, C, Seifert, AISchembecker, G, Wohlgemuth, K
A key enabler for the future success of continuous manufacturing in pharmaceutical and fine chemical production processes is the control of product quality. Since approx. 90% of all small molecular active pharmaceutical ingredients produced involve a crystallization step, a holistic view on its...