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1. Separation and Purification in the Continuous Synthesis of Fine Chemicals and Pharmaceuticals

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   09 Jun 2023 | Contributor(s):: O'Mahony, M, Ferguson, SStelzer, T, Myerson, A

   The use to both chemists and chemical engineers working in flow synthesis, this chapter provides a summary of separation and purification operations that can be applied to flow synthesis reaction streams. Both single and biphasic separations for the liquid phase are detailed. Separation and...

2. Characterization of a Modular Continuous Vacuum Screw Filter for Small-Scale Solid-Liquid Separation of Suspensions

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   09 Jun 2023 | Contributor(s):: Steenweg, C, Seifert, AISchembecker, G, Wohlgemuth, K

   A key enabler for the future success of continuous manufacturing in pharmaceutical and fine chemical production processes is the control of product quality. Since approx. 90% of all small molecular active pharmaceutical ingredients produced involve a crystallization step, a holistic view on its...