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1. Optimization of residence time distribution in RCDG and an assessment of its applicability in continuous manufacturing

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   09 Jun 2023 | Contributor(s):: Wilms, Annika, Kleinebudde, Peter

   Knowledge of residence time is a critical aspect in developing control and material diversion strategies for continuous manufacturing processes in pharmaceutical manufacturing. Dry granulation is a promising continuous granulation technique as it is fast and economical. In this study, a...

2. Experimental determination of residence time distribution in continuous dry granulation

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   09 Jun 2023 | Contributor(s):: Mangal, Haress, Kleinebudde, Peter

   With increasing importance of continuous manufacturing, the interest in integrating dry granulation into a continuous manufacturing line is growing. Residence time distribution measurements are of importance as they provide information about duration of materials within the process. These data...