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Model-based evaluation of direct nucleation control approaches for the continuous cooling crystallization of paracetamol in a mixed suspension mixed product removal system
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09 Jun 2023 | Contributor(s):: Acevedo, David, Yang, Yang Warnke, Daniel J., Nagy, Zoltan K. ;
Direct nucleation control (DNC) is a model-free feedback control approach based on the measurement of particle number in the crystallization process. The experimental implementation has demonstrated that this approach is efficient to produce large and uniform crystals in batch crystallization, or...