Dynamic flowsheet model development and digital design of continuous pharmaceutical manufacturing with dissolution modeling of the final product
Contributor(s):: Nagy, Brigitta, Szilágyi, Botond Domokos, András Vészi, Blanka, Tacsi, Kornélia, Rapi, Zsolt, Pataki, Hajnalka, Marosi, György, Nagy, Zoltán K., Nagy, Zsombor Kristóf
The integration of continuous unit operations imposes a challenge on the pharmaceutical companies aspiring to achieve plant-wide continuous manufacturing due to the additional complexity of the dynamic interactions, process control and quality assurance. To overcome this challenge, flowsheet...