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Have you had challenges with CM adhesion/cohesion? Experts are discussing this topic in the Oral Solid Dosage Group,, broken out into the following key areas: conveying, feeding, transfer hoppers, and transition pipes. Learn from their experience by reading the full conversation here: https://cmkc.usp.org/groups/oralsoliddose/forum/default-section/discussions/111
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Tags: Dynamic modeling

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Resources (1-2 of 2)

  1. Challenges in tracing material flow passing a loss-in-weight feeder in continuous manufacturing processes

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    Contributor(s):: Peterwitz, Moritz, Gerling, Sina, Schembecker, Gerhard

    Loss-in-weight feeders are an integral part of most continuous manufacturing processes, ensuring a constant mass flow. The feeders cause a significant degree of back-mixing in such lines. Understanding back-mixing is essential for the treatment of disturbances. However, feeders refilled...

  2. Anti-fouling control of plug-flow crystallization via heating and cooling cycle

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    Contributor(s):: Koswara, Andy, Nagy, Zoltan K.

    Plug-flow crystallization (PFC) is a promising continuous pharmaceutical crystallization process but is prone to fouling due to uncontrolled crystallization on the reactor surface (encrustation). This results in operational issues such as (1) flow blockage, (2) increased thermal resistance, and...