Technoeconomic MINLP Optimisation of Liquid-Liquid Extraction (LLE) Cascades for Continuous Pharmaceutical Manufacturing (CPM) of Atropine
Contributor(s):: Diab, S, Mytis, NBoudouvis, AG, Gerogiorgis, DL
Continuous pharmaceutical manufacturing (CPM) has the potential to revolutionise the production of active pharmaceutical ingredients (APIs), offering operational and economic benefits over the currently dominant batch methods implemented by industry. Atropine is a nerve agent API, whose...
Development and Application of a Business Case Model for a Stream Sampler in the Pharmaceutical Industry
Contributor(s):: Fontalvo-Lascano, María A, Alvarado-Hernández, Bárbara B., Conde, Carlos, Sánchez, Eric J., Méndez-Piñero, Mayra I., Romañach, Rodolfo
Purpose: A template to prepare a business case for Process Analytical Technology (PAT) and Continuous Manufacturing (CM) projects is presented in this study. Business cases are necessary tools used in different organizations to present new projects for management evaluation. As new ways of...