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3.15.4.204

Tags: Efavirenz

Resources (1-1 of 1)

  1. A Concise Flow Synthesis of Efavirenz

    Contributor(s):: Correia, Camille A., Gilmore, Kerry, McQuade, D. Tyler, Seeberger, Peter H.

    Efavirenz is an essential medicine for the treatment of HIV, which is still inaccessible to millions of people worldwide. A novel, semi-continuous process provides rac-Efavirenz with an overall yield of 45 %. This streamlined proof-of-principle synthesis relies on the efficient copper-catalyzed...