Near-Infrared Spectroscopy for the In-Line Characterization of Powder Voiding Part II: Quantification of Enhanced Flow Properties of Surface Modified Active Pharmaceutical Ingredients
Contributor(s):: Beach, Lauren, Ropero, Jorge, Mujumdar, Ajit, Alcala, Manel, Romanach, Rodolfo J., Dave, Rajesh N.
In this work, dry-particle coating was used to modify the surface properties of active pharmaceutical ingredients (APIs) having extremely poor flow properties. Near-infrared (NIR) spectroscopy was utilized as a novel approach to characterize the improved flow behavior of APIs and their blends....