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  1. Process Modeling Issues in the Design of a Continuous-Flow Process for the Production of Ibuprofen

    Contributor(s):: Tripodi, A, Martinazzo, RRamis, G, Rossetti, I

    The continuous-flow production of active pharmaceutical ingredients is a spreading applicative Research Article field. Process simulation tools are effective means for in silico process design, but care is needed. A paradigmatic example is the synthesis of ibuprofen. First, the most appropriate...