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  1. Continuous twin screw extrusion for the wet granulation of lactose

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    09 Jun 2023 | Contributor(s):: Keleb, EI, Vermeire, A, Vervaet, C, Remon, JP

    The Suitability of continuous twin screw extrusion for the wet granulation of a-lactose monohydrate was studied and compared with conventional high shear granulation. The influence of process parameters (screw speed and total input rate) and formulation variables (water and polyvinylpyrrolidone...