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Tags: Gravimetric

All Categories (1-3 of 3)

  1. New gravimetric dosing device for Continuous Manufacturing

    Website | 18 Jan 2024 | Contributor(s):: VX management

    "So far, it is mainly Loss in Weight feeders (LIW) that are used for this purpose, especially in the pharmaceutical industry, as they can handle smaller flow rates accurately enough. The mechanical concept of these is decades old and despite miniaturisation and improvements at detail...

  2. Process Control of Drug Product Continuous Manufacturing Operations - a Study in Operational Simplification and Continuous Improvement

    Peer-reviewed journal | 09 Jun 2023 | Contributor(s):: Medendorp, Joseph, Shapally, Sreendhar, Vrieze, Derek, Tolton, Kelly

    Purpose The purpose of this manuscript is to demonstrate that implementation of gravimetric measurements provides the same assurance of product quality and process control as spectroscopic measurements (1) for control of drug content in a fixed-dose combination (FDC) tablet and (2) for...

  3. Method for characterization of loss-in-weight feeder equipment

    Peer-reviewed journal | 09 Jun 2023 | Contributor(s):: William E. Engisch, Fernando J. Muzzio 

    This paper presents a method for evaluating the steady state performance of loss-in-weight powder feeding equipment and then demonstrates the use of the method in evaluating the performance of a K-Tron KT35 loss-in-weight feeder for three pharmaceutical grade powders. The method describes in...