Crystallisation and physicochemical property characterisation of conformationally-locked co-crystals of fenamic acid derivatives
Contributor(s):: Wittering, KE, Agnew, LRKlapwijk, AR, Robertson, K, Cousen, AJP, Cruickshank, DL, Wilson, CC
Polymorphism in drug compounds can cause significant problems for industrial-scale production and so a method for restricting the conformational freedom of the target compound whilst retaining desired chemical properties is highly beneficial to the pharmaceutical industry. Co-crystallisation is...