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Tags: Growth & nucleation parameters

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Peer-reviewed journal (1-1 of 1)

  1. Nucleation and Growth Kinetics for Combined Cooling and Antisolvent Crystallization in a Mixed-Suspension, Mixed-Product Removal System: Estimating Solvent Dependency

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    09 Jun 2023 | Contributor(s):: Schall, JM, Mandur, JSBraatz, RD, Myerson, AS

    Combined cooling and antisolvent crystallization is a critical unit operation in pharmaceutical manufacturing, especially for heat-sensitive or poorly soluble active pharmaceutical ingredients. The model-based design of these systems relies on the accuracy of the underlying growth and nucleation...