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Tags: hybrid batch–flow process

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  1. Telescoped Hybrid Batch–Flow Synthesis of 2-Butylbenzofuran

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    25 Jun 2024 | Contributor(s):: Dedè, Fabiana, Ciancimino, Cristina, Danelli, Piero, Piccolo, Oreste, Vigo, Daniele

    The present work describes the development of an improved synthesis of the pharmaceutically relevant building block 2-butylbenzofuran (BBF). The telescoped hybrid batch–flow process is composed of three steps and affords the final product in high yield and purity. The key cyclization step is...