Expedient preparation of active pharmaceutical ingredient ketamine under sustainable continuous flow conditions
Contributor(s):: Kassin, VEH, Gerardy, RToupy, T, Collin, D, Salvadeo, E, Toussaint, F, Van, Hecke, K, Monbaliu, JCM
A robust three-step continuous flow procedure is presented for the efficient and sustainable preparation of active pharmaceutical ingredient ketamine. The procedure relies on the main assets of continuous flow processing, starts from commercially available chemicals, utilizes low toxicity...