Influence of filler selection on twin screw foam granulation
Contributor(s):: Rocca, K. E., Weatherley, S., Sheskey, P. J., Thompson, M. R.
The influence of filler selection in wet granulation was studied for the novel case where the binder is delivered as an unstable, semi-rigid aqueous foam to an extrusion process. The work primarily examined the impact of differing concentrations of microcrystalline cellulose (Avicel PH (R) 101)...
Continuous twin screw extrusion for the wet granulation of lactose
Contributor(s):: Keleb, EI, Vermeire, A, Vervaet, C, Remon, JP
The Suitability of continuous twin screw extrusion for the wet granulation of a-lactose monohydrate was studied and compared with conventional high shear granulation. The influence of process parameters (screw speed and total input rate) and formulation variables (water and polyvinylpyrrolidone...