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1. Non-invasive, continuous, quantitative detection of powder level and mass holdup in a metal feed tube

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   09 Jun 2023 | Contributor(s):: Louge, Michel Y, Mandur, Jasdeep, Blincoe, William, Tantuccio, Anthony, Meyer, Robert F

   We describe a quantitative, non-invasive capacitance detector providing a rapid signal that varies continuously with powder level and/or mass holdup in the metal feed tube of a tablet press. We outline the principle of its processing electronics, provide an algorithm for the accurate...

2. Implementation of control system into continuous pharmaceutical manufacturing pilot plant (powder to tablet)

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   09 Jun 2023 | Contributor(s):: Singh, Ravendra

   Real-time process control is highly desired for efficient quality by design (QbD)-based pharmaceutical manufacturing. A control system ensures the predefined end-product quality, satisfies the high regulatory constraints, facilitates real-time release of the product, and optimizes the resources....