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  1. Flash Chemistry Approach to Organometallic C-Glycosylation for the Synthesis of Remdesivir

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    25 Jun 2024 | Contributor(s):: Keutz, Timo von, Williams, Jason D., Kappe, C. Oliver

    In a rapidly changing environment, such as the current COVID-19 pandemic, continuous flow reactors bear the potential to increase the production of urgently needed active pharmaceutical ingredients (APIs) on demand. In the synthesis of remdesivir, the organometallic C-glycosylation step was...