Modeling-Assisted Design of Thermostable Benzaldehyde Lyases from Rhodococcus erythropolis for Continuous Production of alpha-Hydroxy Ketones
Contributor(s):: Peng, M, Siebert, DLEngqvist, MKM, Niemeyer, CM, Rabe, KS
Enantiopure alpha-hydroxy ketones are important building blocks of active pharmaceutical ingredients (APIs), which can be produced by thiamine-diphosphate-dependent lyases, such as benzaldehyde lyase. Here we report the discovery of a novel thermostable benzaldehyde lyase from Rhodococcus...