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The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry
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09 Jun 2023 | Contributor(s):: Baumann, M, Baxendale, IR
The implementation of continuous flow processing as a key enabling technology has transformed the way we conduct chemistry and has expanded our synthetic capabilities. As a result many new preparative routes have been designed towards commercially relevant drug compounds achieving more efficient...
Intelligent Alarm Management Applied to Continuous Pharmaceutical Tablet Manufacturing: An Integrated Approach
09 Jun 2023 | Contributor(s):: Gupta, Anshu, Giridhar, Arun, Venkatasubramanian, Venkat., Reklaitis, Gintaras V.
One important aspect of effective real time process management is the implementation of intelligent systems that can assist human operators in making supervisory control decisions. Conventional practice is to simply sound alarms when process variables go out of range leaving it to the operator to...