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  1. Cleaning of direct compression continuous manufacturing equipment through displacement of API residues by excipients

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    23 Jul 2024 | Contributor(s):: Patel, Dhavalkumar S, Méndez, Rafael, Romañach, Rodolfo J

    This feasibility study evaluates a cleaning process designed to avoid the use of detergents and reduce operator exposure to the active pharmaceutical ingredient (API). The continuous manufacturing equipment was cleaned using excipients to displace ibuprofen residues from the system. The cleaning...