Mechanistic modeling and parameter-adaptive nonlinear model predictive control of a microbioreactor
09 Jun 2023 | Contributor(s):: Hong, Moo Sun, Braatz, Richard D.
Microbioreactors are a promising technology to accelerate biologic drug development. In aerobic cellular respiration, a potential limit to the productivity of such systems is the transport of oxygen from an external gas to the most oxygen-deficient cells, and the potential for excessive spatially...
A design aid for crystal growth engineering
09 Jun 2023 | Contributor(s):: Li, Jinjin, Tilbury, Carl J. Kim, Seung Ha, Doherty, Michael F.
With the highly competitive development of chemical and pharmaceutical industries, mastering crystal growth is becoming increasingly necessary. Modern industrial manufacturers place high importance on the ability to grow crystals with a specific habit using tailored operating conditions. A...