All Categories (1-3 of 3)

1. The Concept of Chemical Generators: On-Site On-Demand Production of Hazardous Reagents in Continuous Flow

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   09 Jun 2023 | Contributor(s):: Dallinger, D, Gutmann, B, Kappe, CO

   CONSPECTUS: In recent years, a steadily growing number of chemists, from both academia and industry, have dedicated their Research Article to the development of continuous flow processes performed in milli- or microreactors. The common availability of continuous flow equipment at virtually all...

2. Nanofiltration-Enabled InSitu Solvent and Reagent Recycle for Sustainable Continuous-Flow Synthesis

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   09 Jun 2023 | Contributor(s):: Fodi, T, Didaskalou, CKupai, J, Balogh, GT, Huszthy, P, Szekely, G

   Solvent usage in the pharmaceutical sector accounts for as much as 90% of the overall mass during manufacturing processes. Consequently, solvent consumption poses significant costs and environmental burdens. Continuous processing, in particular continuous-flow reactors, have great potential for...

3. Characterization and Modeling of the Operating Curves of Membrane Microseparators

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   09 Jun 2023 | Contributor(s):: Yang, L, Weeranoppanant, N, Jensen, KF

   The membrane microseparator is a milliliter-scale flow chemistry module that continuously separates a biphasic flow through a PTFE microporous membrane. It has found a wide range of applications in the continuous manufacturing of active pharmaceutical ingredients and fine chemicals, especially...