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  1. Metabolic Engineering: The Ultimate Paradigm for Continuous Pharmaceutical Manufacturing

    Contributor(s):: Yadav, VG, Stephanopoulos, G

    Research Article and development (R&D) expenditures by pharmaceutical companies doubled over the past decade, yet candidate attrition rates and development times rose markedly during this period. Understandably, companies have begun downsizing their pipelines and diverting investments away from...