Application of process analytical technology-based feedback control for the crystallization of pharmaceuticals in porous media
Contributor(s):: Acevedo, David A., Ling, Jing Chadwick, Keith, Nagy, Zoltak K. ;
The purpose of this work is to implement a feedback control approach during the cooling crystallization of paracetamol (PCM) in porous media to increase the amount of PCM in the alginate beads (i.e., drug loading) and minimize the heterogeneous nucleation occurring in the bulk system. Two types...