Intermolecular hydrogen transfer and solubility tuning in multi-component molecular crystals of the API piroxicam
Contributor(s):: Thomas, LH, Klapwijk, ARWales, C, Wilson, CC
A series of twelve multi-component molecular crystals of the active pharmaceutical ingredient (API) piroxicam (PX) have been synthesised and their structures analysed with respect to their supramolecular motifs and degree of intermolecular hydrogen transfer observed on formation of the various...