Complexation-Assisted Continuous Crystallization of Isomeric Systems with Nanofiltration Recycle
Contributor(s):: Vartak, S, Myerson, AS
In API-impurity systems consisting of structural isomers, the impurity has a strong affinity to incorporate into the host crystal owing to their identical molecular weight and similar structure. Conventional successive recrystallization turns out to be an unattractive purification strategy in...