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Tags: ontinuous flow process

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  1. Continuous flow synthesis of the URAT1 inhibitor lesinurad

    10 May 2024 | Contributor(s):: Damião, Mariana C. F. C. B., Marçon, Henrique M., Pastre, Julio Cezar

    Herein, the urate anion exchange transporter 1 (URAT1) inhibitor lesinurad is synthesized from commercially available building blocks by a five-step linear continuous flow sequence. Our previously developed continuous flow platform was successfully applied to generate the 3-thio-1,2,4-triazole...